Analysis of IL-1β, CXCL8, and TNF-α levels in the crevicular fluid of patients with periodontitis or healthy implants

Abstract Background Our study aimed to assess the level of IL-1β, CXCL8, and TNF-α in peri-implant sulcular fluid (PISF) collected from patients with no clinical symptoms mucositis or peri-implantitis compare them cytokine concentration gingival crevicular (GCF) acquired healthy periodontium those varying severity periodontitis. Methods A total 189 subjects were included study, GCF/PISF samples checked for levels using an ELISA test. Results The IL-1β PISF implants was significantly lower than GCF mild, moderate, severe CXCL8 considerably moderate markedly higher compared mild Conclusion Analysis may help describe pathogenesis early diagnosis prevision high-risk patients.